Here are a few basic tips for optimizing your ad layout, and your page layout for adsense.

• Most people are reporting that medium or large rectangles near the top of your page will have the highest click through rate. Skyscraper ads on the right are also very popular.
  
  You can actually put a leaderboard at the top, a skyscraper on the right (of left), and another leaderboard at the bottom. This gives you're visitors plenty of tempting adsense ads to click through.

• Instead of having a site with multiple subjects you can try using separate domain names for each subject. There are people with 20 sites, or even more.
  
  By separating your info over multiple web sites, each with their own domain name, you will be able to market and optimize each individual site.
  
  
• Be sure to make your ads match your site, and make the border color the same as the background color if you can. We’ve heard that this can increase your percentages, and it just plain looks good.
  
  
• Recently someone said that using heading tags with your keywords helps adsense target ads for your content... this might be worth a try.

Go back to the Adsense Tips page.